Older publications


Chasman DI, Fuchsberger C…Wheeler HE…Kao WH, Fox CS, Kottgen A (>100 authors) (2012) Integration of genome-wide association studies with biological knowledge identifies six novel genes related to kidney function. Human Molecular Genetics 21(24):5329-43. PMC3607468

Cox NJ, Gamazon ER, Wheeler HE, Dolan ME (2012) Clinical translation of cell-based pharmacogenomic discovery. Clinical Pharmacology & Therapeutics 92(4):425-7. PMC3664667

Madian AG, Wheeler HE, Jones RB, Dolan ME (2012) Relating human genetic variation to variation in drug responses. Trends in Genetics 28(10):487-95. PMC3448823

Stark AL, Delaney SM, Wheeler HE, Im HK, Dolan ME (2012) Functional consequences of PRPF39 on distant genes and cisplatin sensitivity. Human Molecular Genetics 21(19):4348-55. PMC3441128

Leandro-Garcia LJ, Lekela S, Jara Sanchez C, Green H, Avall Lundqvist E, Wheeler HE, Dolan ME, Inglada-Perez L, Maliszewska A, de Cubas AA, Comino-Mendez I, Mancikova V, Cascon A, Robledo M, Rodriguez-Antona C (2012) Regulatory polymorphisms in β-tubulin IIa are associated with paclitaxel-induced peripheral neuropathy. Clinical Cancer Research 18(16):4441-8. PMC3664665

O’Donnell PH, Stark AL, Gamazon ER, Wheeler HE, McIlwee BE, Gorsic LK, Im HK, Huang RS, Cox NJ, Dolan ME (2012) Identification of novel germline polymorphisms governing capecitabine sensitivity. Cancer 118(16):4063-73. PMC3413892

Pattaro C, Köttgen A, Teumer A, Garnaas M, Böger CA…Wheeler HE…Kao WH, Fox CS (>100 authors) (2012) Genome-wide association and functional follow-up reveals new loci for kidney function. PLoS Genetics 8(3): e1002584. PMC3315455

Njiaju UO, Gamazon ER, Gorsic LK, Delaney SM, Wheeler HE, Im HK, Dolan ME (2012) Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel. Pharmacogenetics and Genomics 22(7): 498-507. PMC3376193

Wheeler HE and Dolan ME. (2012) Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation. Pharmacogenomics 13(1):55-70. PMC3292907


Wheeler HE, Gorsic LK, Welsh M, Stark AL, Gamazon ER, Cox NJ, Dolan ME. (2011) Genome-wide local ancestry approach identifies genes and variants associated with chemotherapeutic susceptibility in African Americans. PLoS One 6(7): e21920. PMC3130766

Wen Y, Gorsic LK, Wheeler HE, Ziliak DM, Huang RS, Dolan ME. (2011) Chemotherapeutic-induced apoptosis: a phenotype for pharmacogenomics studies. Pharmacogenetics and Genomics 21(8): 476-88. PMC3134538

Wheeler HE and Kim SK (2011) Genetics and genomics of human ageing. Philosophical Transactions of the Royal Society B 366(1561): 43-50. PMC3001305


Wheeler HE, Metter EJ, Tanaka T, Absher D, Higgins J, Zahn JM, Wilhelmy J, Davis RW, Singleton A, Myers RM, Ferrucci L, Kim SK. (2009) Sequential use of transcriptional profiling, expression quantitative trait mapping and gene association implicates MMP20 in human kidney aging. PLoS Genetics 5(10): e1000685. PMC2752811